منابع مشابه
Augmentation of aortic ring contractions by angiotensin II antisense peptide.
Previous biochemical experiments have revealed two antisense peptide antagonists to human angiotensin II (Ang II), one encoded in the cDNA in the antiparallel reading, the other in the parallel reading. Neither peptide's ability to produce physiological antagonism has been demonstrated previously. Both peptides were tested for their ability to antagonize Ang II-induced contractions on rabbit ao...
متن کاملRNA polymerase II synthesizes antisense RNA in Plasmodium falciparum.
The recent identification of antisense RNA in the transcriptomes of many eukaryotes has generated enormous interest. The presence of antisense RNA in Plasmodium falciparum, the causative agent of severe malaria, remains controversial. Elucidation of the mechanism of antisense RNA in P. falciparum synthesis is critical in order to demonstrate the origin and function of these transcripts. Therefo...
متن کاملAntisense of human peroxiredoxin II enhances radiation-induced cell death.
Human peroxiredoxin II (Prx II) has been known to function as an antioxidant enzyme in cells. Using head-and-neck cancer cell lines, we investigated whether Prx II expression is related to the resistance of cells to radiation therapy in vivo and in vitro, and whether a Prx II antisense serves as a radiosensitizer. Increased expression of Prx II was observed in tissues isolated from the patients...
متن کاملAntisense Technology and its Implications Gene Expression Antisense Technology The Design and Targeting of Antisense ODNs
While many studies have examined the numerous physiological and pharmacological factors which can induce the expression of c-fos and other immediate-early genes, few have examined the consequences of altering their expression pattern. Using antisense oligonucleotides to c-fos, we demonstrate that amphetamine-induced c-fos expression c m be attenuated in vivo, in specific brain regions. This uni...
متن کاملAntisense ribosomes: rRNA as a vehicle for antisense RNAs.
Although rRNA has a conserved core structure, its size varies by more than 2000 bases between eubacteria and vertebrates, mostly due to the size variation of discrete variable regions. Previous studies have shown that insertion of foreign sequences into some of these variable regions has little effect on rRNA function. These properties make rRNA a potentially very advantageous vehicle to carry ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nervenheilkunde
سال: 2018
ISSN: 0722-1541,2567-5788
DOI: 10.1055/s-0038-1675711